Skill in shaping discovery
Performing high quality PK studies and ADME profiling assists clients in prioritizing leads and maximizing efficiencies while keeping in step with timelines. Among the various standard and specialized In Vivo studies are:
Standard pharmacokinetics determinations in conscious rats, mice and guinea pigs.
Carotid artery and jugular vein catheterized rats and guinea pigs with intra-duodenal dosing.
Carotid artery, jugular vein and bile duct catheterized rats and guinea pigs.
Hepatoportal and jugular vein catheterized rats and guinea pigs.
Serial collection of plasma and cerebrospinal fluid (CSF) in freely moving rats.
Microdialysis studies in rats, guinea pigs and mice.
