Services : DMPK : In Vivo Pharmacokinetics : Preclinical Cro : Noabbiodiscoveries.com

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In Vivo Studies
Pharmacokinetics studies in:

Pharmacokinetics determinations in rats, mice, and guinea pigs
Carotid artery and jugular vein catheterized rats with intra-duodenal dosing
Carotid artery, jugular vein and bile duct catheterized rats and guinea pigs
Hepatoportal vein catheterized rats
Serial collection of plasma and cerebrospinal fluid (CSF) in freely moving rats.
Microdialysis in Freely Moving Rats.
Cannulated Mouse PK

In Vitro Assays

Cell permeability assays
Plasma protein binding
Cytochrome P450 induction studies
Cytochrome P450 enzyme subtype inhibition studies
Metabolic stability in hepatocytes
Metabolic stability in liver subcellular fractions
Plasma stability assays
Cytotoxicity assays
Customer specific screening assays (radiochemical, fluorescent, etc.)

DTEx™ Services