In Vivo Studies
Pharmacokinetics studies in:
Pharmacokinetics studies in:
- Pharmacokinetics determinations in rats, mice, and guinea pigs
- Carotid artery and jugular vein catheterized rats with intra-duodenal dosing
- Carotid artery, jugular vein and bile duct catheterized rats and guinea pigs
- Hepatoportal vein catheterized rats
- Serial collection of plasma and cerebrospinal fluid (CSF) in freely moving rats.
- Microdialysis in Freely Moving Rats.
In Vitro Assays
DTEx™ Services
- Cell permeability assays
- Plasma protein binding
- Cytochrome P450 induction studies
- Cytochrome P450 enzyme subtype inhibition studies
- Metabolic stability in hepatocytes
- Metabolic stability in liver subcellular fractions
- Plasma stability assays
- Cytotoxicity assays
- Customer specific screening assays (radiochemical, fluorescent, etc.)
DTEx™ Services
