When you need quality, efficient and timely drug discovery services, NoAb BioDiscoveries is the preclinical CRO (contract research organization) for you! At www.noabbiodiscoveries.com you will find a wide range of specialized and standard research services to help you shape and optimize your drug discovery research. NoAb BioDiscoveries has a research facility located in the heart of one of North America's key biotech hubs made up of a team of expert scientists and state-of-the-art instrumentation and technology. This pre-clinical CRO is a cutting edge provider of highly innovative and advanced research tools that accelerate the timelines associated with identifying viable and optimal clinical candidates and achieve success. The range of discovery services on offer at www.noabbiodiscoveries.com includes in vivo pharmacokinetics (PK) studies, in vitro ADME assays, bioanalytical services and gene expression assays.
As a preclinical CRO that is committed to accelerating the drug discovery process, reducing cost and maximizing success, NoAb BioDiscoveries develops advanced research tools that better characterize the pharmacokinetic properties of new drug candidates, optimizing the selection of viable clinical candidates. The organization focuses its efforts on lead selection and optimization and all its discovery services are geared at providing clients with reliable and accurate information through superior scientific procedures. Clients are afforded the ability to profile compounds for selection of the best candidates for further pre-clinical and clinical development. In vivo PK studies include studies in carotid artery and jugular vein catheterized rats with intra-duodenal dosing, carotid artery, jugular vein and bile duct catheterized rats and guinea pigs, hepatoportal vein catheterized rats, serial collection of plasma and cerebrospinal fluid (CSF) in freely moving rats and microdialysis. In vitro ADME profiling involves assays on cell permeability, plasma protein binding, cytochrome P450 subtype inhibition, metabolic stability in hepatocytes and liver subcellular fractions, plasma stability and cytotoxicity.
All the studies are carried out at the preclinical CRO's research facility under strict guidelines that may not be GLP guidelines but are performed under the same spirit with the proper controls. The government-approved vivarium houses small rodents, including rats and mice that have been appropriately cannulated for drug administration and sample collection. The highly trained and experienced scientists skillfully perform all standard and specialized protocols in accordance with customer specifications and have the ability to design the best strategies and protocols for any drug discovery needs. When you use discovery services from NoAb BioDiscoveries you can be assured that your drug discovery research will be successful and reduce your costs! NoAb BioDiscoveries is committed to developing long-term relationships with its clients and will put in every effort to ensure 100% customer satisfaction; make sure to choose this preclinical CRO as your number one partner in drug discovery research.
NoAb BioDiscoveries is a dynamic preclinical CRO that constantly uses innovation to improve the future of drug discovery research and continue on the path to delivering premier drug discovery services to its clients. Using the specialized and proprietary research services available, you can achieve success and accelerate timelines required to select and optimize leads for further preclinical and clinical development. All the data generated is accurate and reliable allowing you to select only the best candidates that will be successful in clinical trials every time; choose NoAb BioDiscoveries and stay ahead of the competition!
