NoAb BioDiscoveries provides a wide range of specialized in proprietary research services. All work conducted by the facility is carried out to be stricter standards, both scientific and ethical, ensuring the most reliable results. The 12,600 ft.² facility is located in Mississauga Ontario, one of the key biotech centers in the world.
ADME stands for Absorption, Distribution, Metabolism, and Excretion, and refers to testing commonly conducted in pharmacokinetic and pharmacological studies. It describes the disposition of a pharmaceutical compound within an organism and is one of the traditional approaches towards early appraisal of factors that impact the success of a drug candidate in the subsequent preclinical, clinical and commercial phases of drug development.
In modern usage, however, ADME and PK studies are part of an overall approach to drug research and preclinical ADME has become a mature discipline through the utilization of in vivo and in vitro methodologies. These methodologies involving preclinical ADME studies are available at NoAb BioDiscoveries, a high-tech research facility that offers a wide range of drug discovery services and systems designed to expedite the drug development process. Through this selection of specialized and proprietary services, NoAb BioDiscoveries helps to shape and optimize drug discovery research by providing innovative tools that facilitate success without compromising on the reliability or accuracy of the study. Through this approach, optimal and viable drug candidates are developed in a timely manner, ensuring your success.
Clients of NoAb BioDiscoveries can analyze compounds for selection of the best candidates for further pre-clinical and clinical development as a result of in vivo and in vitro studies and gene expression assays. The group of experienced scientists at this respected research facility is expert at designing the most effective strategy and protocols to meet any drug discovery need. Studies are skillfully designed and performed as standard procedures or tailored to each client's needs and involve using fully conscious specimens that have been prepared for drug administration and sample collection in adherence to strict scientific and ethical guidelines. To review study records and studies previously done by NoAb BioDiscoveries, browse through www.noabbiodiscoveries.com where detailed information is available on various case studies. A full list of the services offered, which include preclinical ADME/PK studies and gene expression, is also available on the site.
The high quality and highly effective preclinical ADME testing at NoAb BioDiscoveries helps to select and prioritize leads. In conjunction with the results of toxicity analysis, hits from high throughput screening can be developed into leads which can then be optimized into promising drug candidates. Through ADME/PK profiling such as cell permeability and plasma protein binding, investigators have been able to see the impact of drug treatments in pre-clinical and clinical models and identify potential drug candidates. NoAb BioDiscoveries is committed to continue on the path of premier drug discovery so as to consistently deliver the best results to its clients!
Trust NoAb BioDiscoveries to find you the most promising drug candidates using highly effective technologies such as preclinical ADME profiling in the shortest time possible and with the greatest efficiency. No one understands better than NoAb BioDiscoveries that its success is entirely dependent on your success. For further information on the extensive range of in vivo and in vitro services conducted by the facility, visit www.noabbiodiscoveries.com. If you need a drug design strategy tailored to your specifications, you can contact the research facility with details at info@noabbiodiscoveries.com.
