Pharmacokinetic or PK studies are performed to determine the fate of substances administered externally to an organism such as drugs and involves but is not limited to studies on the extent or rate of Absorption, Distribution, Metabolism and Excretion which is commonly refereed to as ADME. PK studies explore what the body does to a drug and are carried out by non-compartmental or compartmental methods. There are a number of techniques employed in PK studies such as mass spectrometry or bioanalytical methods. NoAb BioDiscoveries is one of the leading research facilities in North America that specializes in in vivo PK studies, in vitro ADME assays and gene expression assays to deliver competitive drug discovery services to its clients. The research facility houses state-of-the-art technology and expert scientists that help to shape and optimize drug discovery research by focusing on lead selection and optimization.
Using specialized and proprietary research services that are continually being developed and improved upon, NoAb BioDiscoveries accelerates the drug development process to offer success and shorter timelines in the production of optimal and viable candidates. Innovative tools have been designed to carry out PK studies and ADME profiling that produce the best strategy and protocols to suit any drug discovery need. The development of viable leads that can be further optimized into promising drug candidates allows the company's clients to achieve success consistently. At NoAb BioDiscoveries, PK studies are skillfully designed and performed as standard protocols or specialized according to a client's specifications to deliver high quality and high efficiency services. PK studies typically involve the use of fully conscious animals that have been appropriately catheterized for drug administration and sample collection. All the procedures are carried out by highly trained and experienced scientists in adherence to strict guidelines and ethics ensuring quality, efficiency and timeliness.
PK studies at NoAb BioDiscoveries involve pharmacokinetics determinations in mice and rats. At www.noabbiodiscoveries.com you will find comprehensive information on PK studies in carotid artery and jugular vein catheterized rats with intra-duodenal dosing, carotid artery, jugular vein and bile duct catheterized rats and guinea pigs, hepatoportal vein catheterized rats, serial collection of plasma and cerebrospinal fluid (CSF) in freely moving rats and microdialysis. You can also view study records and examine case studies of previous projects at www.noabbiodiscoveries.com. The company's goal is to continuously develop advanced research tools to better characterize the pharmacokinetic properties of drug candidates, optimizing the selection of viable clinical candidates and NoAb BioDiscoveries has consistently delivered outstanding services to its clients by following the path of premier drug discovery services.
Success in drug discovery may seem a formidable task but with NoAb BioDiscoveries joining you in the path to clinical drug design that leads to optimal candidates in an efficient and timely manner, you can achieve success in drug discovery research. The comprehensive and specialized range of services that included specialized PK studies and ADME profiling together with micro array based technologies will result in a reduction of cost while maximizing your success. Contact NoAb BioDiscoveries at info@noabbiodiscoveries.com with your specific requirements and let the experts design the best strategy and protocols to suit your drug discovery needs!
