Located in a 12,600 ft.² facility in Mississauga, Ontario, NoAb BioDiscoveries offers a wide range of drug discovery services, including in vivo and in vitro testing, bioanalytical services, DTEx technology and pharmacokinetic determinations. NoAb BioDiscoveries is renowned as a pioneer in the drug discovery field, and is committed to continuing to develop new and innovative approaches.
ADME studies are among NoAb BioDiscoveries key services. ADME is an acronym commonly used in pharmacokinetic (PK) studies and pharmacology that stands for Absorption, Distribution, Metabolism and Excretion. ADME describes the way that a pharmaceutical substance is processed within an organism and what is typically used in the early phases of drug study to determine the safety and effectiveness of a substance before clinical trials.
Today, however,
ADME studies are used in conjunction to design a rational approach to drug research and preclinical ADME has become a mature discipline through the in vitro and in vivo methodologies. These methodologies involving preclinical ADME studies are available at NoAb BioDiscoveries, a high-tech research facility that offers a wide range of drug discovery services and systems geared towards the acceleration of the drug development process. Through this selection of specialized and proprietary services, NoAb BioDiscoveries assists you in shaping and optimizing drug research by developing innovative tools that facilitate success without compromising on the accuracy or reliability of the research. In this manner, safe and effective drug candidates are produced in a timely manner, ensuring your success.
Clients of NoAb BioDiscoveries can review compounds for selection of the best candidates for further pre-clinical and clinical development as a result of in vivo and in vitro studies and gene expression assays. The team of experienced researchers at this respected research facility is experienced in creating the best approach and protocols to meet any drug discovery need. Studies are skillfully designed and conducted as standard procedures or tailored to each client's needs and involve using live animals that have been catheterized for drug administration and sample collection in accordance with strict ethical and scientific guidelines. To investigate study records and studies previously done by NoAb BioDiscoveries, browse through www.noabbiodiscoveries.com where in-depth information is available on various case studies. A detailed list of the available services that include
ADME studies and gene expression is also available at www.noabbiodiscoveries.com.
The high quality and innovative
ADME studies at NoAb BioDiscoveries help to identify and prioritize leads. In conjunction with the results of toxicity evaluations, hits from high throughput screening can be expanded into leads which can then be optimized into promising drug candidates. Through ADME/PK profiling such as cell permeability and plasma protein binding, investigators have been able to survey the effects of drug treatments in pre-clinical and clinical models and identify potential drug candidates. NoAb BioDiscoveries is committed to continue on the path of premier drug discovery so as to consistently deliver the best results to its clients!
Rely on NoAb BioDiscoveries to find you the most promising drug candidates using innovative technologies such as ADME/PK profiling in the shortest time possible and with the greatest reliability. Nobody understands better than NoAb BioDiscoveries that its success is entirely dependent on your success. For additional information on the extensive range of in vivo and in vitro services available from the facility, visit www.noabbiodiscoveries.com. If you are looking for a drug design strategy tailored to your specifications, you can contact the research facility with details at info@noabbiodiscoveries.com.
